League Cup
Third round
Liverpool
24 Sep
05:00
(AEST)
Southampton

Liverpool vs Southampton: prediction & betting odds 24 Sep 2025

The English League Cup Round of 16 match between Liverpool and Southampton will take place on September 23 at Anfield. Liverpool vs. Southampton: prediction and betting odds, statistics.

Liverpool

Arne Slot's side, like other teams in the European competition zone, are starting in the Cup only from this round. Last season, the team reached the final but lost to Newcastle 1-2. It is also worth noting that since 2022, Liverpool has won this tournament twice more (both times defeating Chelsea in the final).

  • The club has suffered only 2 defeats in regular time in their last 12 games in this tournament (8 wins and 2 draws).
  • At least 3 goals were scored in 90 minutes in 5 of Liverpool's last 6 League Cup encounters.
  • Both teams scored in regular time in 10 of Liverpool's last 12 matches in this tournament.

Predicted lineup for Liverpool (3-4-3)

Alisson Becker – Milos Kerkez, Ibrahima Konate, Virgil van Dijk – Alexis Mac Allister, Dominik Szoboszlai, Cody Gakpo, Ryan Gravenberch – Mohamed Salah, Florian Wirtz, Hugo Ekitike.

Southampton

The team has already gone through two stages. Playing away, the club secured clean-sheet victories over two opponents: Northampton Town (1-0) and Norwich (3-0). Last season, Southampton reached the quarter-finals, where they lost at home to Liverpool 1-2. It's also worth mentioning that in 2017 the team reached the League Cup final, and in 2023 they made it to the semi-finals.

  • In the last six encounters in this tournament, the club has suffered only 1 defeat in regular time (4 wins and 1 draw).
  • Both teams scored in 90 minutes in 6 of Southampton's last 8 League Cup matches.
  • At least 3 goals were scored in regular time in 6 of the team's last 8 games in this tournament.

Predicted lineup for Southampton (4-2-3-1)

Gavin Bazunu – Jack Stephens, Taylor Harwood-Bellis, Ryan Manning, Mads Roerslev – Shea Charles, Flynn Downes – Ryan Fraser, Finn Azaz, Tom Fellows – Cameron Archer.

Liverpool vs. Southampton: Match Prediction

Liverpool has an excellent record against this opponent. In the last 9 official meetings, Liverpool has secured 8 wins and 1 draw. However, they have only won by a margin of 4 or more goals once in the last 10 head-to-head encounters in the Premier League and two national cups.

Considering their commitments in the Champions League and Premier League, Arne Slot will rotate his squad, allowing us to see young talents and bench players in this match. This will help the visitors avoid a heavy defeat. Moreover, in their last 21 matches in this tournament, Liverpool has only achieved 2 wins with a margin of 4 or more goals. Meanwhile, Southampton has not lost by a large margin in 30 consecutive matches in this tournament.

My prediction – Southampton with a handicap (+3)

Liverpool vs Southampton Odds

1X2
DOUBLE CHANCE
OVER/UNDER
BTTS
TOTAL HOME GOALS
TOTAL AWAY GOALS

League Cup: previous matches of the tournament

Liverpool
The team hasn't played a game yet this season
Southampton
27.08.25
Norwich
Southampton
W
13.08.25
Northampton Town
Southampton
W
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H2H: Liverpool — Southampton

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Premier League 2019-2020
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Premier League 2018-2019
06.04.19
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Premier League 2017-2018
12.02.18
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19.11.17
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Premier League 2016-2017
07.05.17
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Premier League 2015-2016
21.03.16
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26.10.15
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Premier League 2014-2015
23.02.15
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17.08.14
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Premier League 2013-2014
01.03.14
Southampton
Liverpool
0
:
3
21.09.13
Liverpool
Southampton
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:
1
Premier League 2012-2013
16.03.13
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Liverpool
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:
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01.12.12
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Southampton
1
:
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Premier League 2004-2005
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:
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:
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Team lineups

The line-ups will be known a few hours before kick-off
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